尿素和二甲基亚砜诱导DhaA变性的分子动力学模拟
郑禾1(
),杨盛江2,郑永超1,崔燕1,郭旋1,钟近艺1(),周健2()
),杨盛江2,郑永超1,崔燕1,郭旋1,钟近艺1(),周健2()
Molecular dynamics simulation of denaturation of DhaA induced by urea and dimethyl sulfoxide
He ZHENG1(),Shengjiang YANG2,Yongchao ZHENG1,Yan CUI1,Xuan GUO1,Jinyi ZHONG1(),Jian ZHOU2()
),Shengjiang YANG2,Yongchao ZHENG1,Yan CUI1,Xuan GUO1,Jinyi ZHONG1(),Jian ZHOU2()
图8. DhaA在模拟体系中催化位点的结构变化（蓝色为纯水体系中的DhaA，红色为尿素体系中的DhaA，橙色为DMSO体系中的DhaA）
Fig.8. Structural change of catalytic sites of DhaA in different simulation systems(blue part represents DhaA in water, red part represents DhaA in urea solution, orange part represents DhaA in DMSO solution)
