关键词: 不合格颗粒, 压片, 对乙酰氨基酚, 提取工艺, 生产实施

Abstract: An extraction technology was developed and optimized through physical and chemical properties analysis on each component in unqualified granule for the press of paracetamol tablet. Sample was dissolved in 95% ethanol at 40—50 ℃ for 30 minutes，the suspension was cooled to 20℃ and filtered，the concentratedfiltrate was dissolved in deionized water，decolored and vacuum filtered while hot，then the filtrate was cooled to room temperature，paracetamol was extracted after vacuum filtering and drying. Production implementationwith this extraction technology can be more than 89%，with considerable economic benefit and no environmental pollution associated.

Key words: unqualifiedgranule, tabletting, paracetamol, extraction technology, production implementation