Abstract: Fine ginger oil was extracted with supercritical carbon dioxide （SC-CO2）. A procedure of rapid pressure reduction was designed in order to break the cell wall and reduce the resistance of mass transfer. Using the method of orthogonal design L18（37），the optimum parameters were obtained under the fragmentation pressure of 20.0 MPa，isobaric time of 30min，pressure reduction of 10 MPa/min，extraction pressure of 16.0MPa，extraction temperature of 45.0℃ and extraction time of 60min when the flux of CO2 was 20 m3/h. Compared with the method of Soxlet extraction，this method achieved a higher yield （about 3.62%），Compared with SC-CO2 extraction，the extractipn pressure，temperature and time were reduced obviously in this process，and the yield increased by 1.32 times. Base on these parameters，a pilot scale equipment was designed and fine ginger oil could be extracted with SC-CO2 by running over 4000 hours.