Abstract: The advances in the synthesis and application of the mesoporous sieves are summarized in this paper. The methods of synthesis and modification of mesoporous molecular sieves in the different families of MCM，HMS，MSU，SBA，etc. are introduced. For example，heteroatom doping，grafting organic group，pre-disposal of silica resource，mixed templates result in good catalytic performance and selective oxidation properties of mesoporous molecular sieves. The performance and characteristics of some novel mesoporous molecular sieves are introduced. The present application of mesoporous molecular sieves in chemical industry is reviewed.