CIESC Journal

• Volume 4 • 上一篇    下一篇

THEORY FOR STEP AND PULSE METHOD OF SUPERCRITICAL FLUID CHROMATOGRAPHY

赵锁奇; 王仁安; 杨光华   

  1. State Key Laboratory Heavy Oil Processing, University of Petroleum, Beijing 102200, China
  • 收稿日期:1995-06-16 修回日期:1995-10-31 出版日期:1996-12-28 发布日期:1996-12-28
  • 通讯作者: 赵锁奇

THEORY FOR STEP AND PULSE METHOD OF SUPERCRITICAL FLUID CHROMATOGRAPHY

ZHAO Suoqi; WANG Renan; YANG Guanghua   

  1. State Key Laboratory Heavy Oil Processing, University of Petroleum, Beijing 102200, China
  • Received:1995-06-16 Revised:1995-10-31 Online:1996-12-28 Published:1996-12-28
  • Contact: ZHAO Suoqi

摘要: The paper presents a general retention formula for supercritical fluid chromatography at finite concentration. A new chromatographic rate theory based on the fugacities of solutes instead of concentrations is developed, thus relieving the restrictions of linear isothermal distribution and infinite dilution. An expression for retention values of a N component system including solvent is obtained by combining the rate theory with the mass balance equation of solutes in chromatography. It is shown that there are N-1 characteristic retention peaks for N components and the retention time can be calculated directly from the equilibrium properties of the components in both mobile phase and stationary phase at the given conditions. The theory can be reduced to the well known formula for infinite dilution and to the result of step-pulse theory in gas chromatography under low pressure at finite concentration. Supercritical fluid chromatography may eventually prove itself to be a useful reseach tool in the field of phase equilibrium and thermodynamic properties of supercritical fluid system.

关键词: supercritical fluid;chromatography;fugacity;step and pulse;finite concentration;retention time

Abstract: The paper presents a general retention formula for supercritical fluid chromatography at finite concentration. A new chromatographic rate theory based on the fugacities of solutes instead of concentrations is developed, thus relieving the restrictions of linear isothermal distribution and infinite dilution. An expression for retention values of a N component system including solvent is obtained by combining the rate theory with the mass balance equation of solutes in chromatography. It is shown that there are N-1 characteristic retention peaks for N components and the retention time can be calculated directly from the equilibrium properties of the components in both mobile phase and stationary phase at the given conditions. The theory can be reduced to the well known formula for infinite dilution and to the result of step-pulse theory in gas chromatography under low pressure at finite concentration. Supercritical fluid chromatography may eventually prove itself to be a useful reseach tool in the field of phase equilibrium and thermodynamic properties of supercritical fluid system.

Key words: supercritical fluid, chromatography, fugacity, step and pulse, finite concentration, retention time