CIESC Journal

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一种分离纯化天然药物紫杉醇的新方法

肖剑; 韩金玉; 马沛生   

  1. College of Chemical Engineering, Tianjin University, Tianjin 300072, China
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2002-12-28 发布日期:2002-12-28
  • 通讯作者: 肖剑

A New Method for Isolating and Purifying Natural Drug Taxol

XIAO Jian; HAN Jinyu; MA Peisheng   

  1. College of Chemical Engineering, Tianjin University, Tianjin 300072, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2002-12-28 Published:2002-12-28
  • Contact: XIAO Jian

摘要: A pharmacological interaction target (PIT) method for solving the difficult problem in the
separation of taxol from cephalonmanine was proposed. A two-phase extraction technique was
used to carry out the PIT separation process. The effects of buffer, temperature and
protein on the separation were investigated. Feasible disassembly conditions were also
discussed. The final purity of taxol can reach 95% or higher.

关键词: taxol;purification;pharmacological interaction target method

Abstract: A pharmacological interaction target (PIT) method for solving the difficult problem in the
separation of taxol from cephalonmanine was proposed. A two-phase extraction technique was
used to carry out the PIT separation process. The effects of buffer, temperature and
protein on the separation were investigated. Feasible disassembly conditions were also
discussed. The final purity of taxol can reach 95% or higher.

Key words: taxol, purification, pharmacological interaction target method