Abstract: For further improving the representation of vapor-liquid equilibrium data, a local-composition version of the Cubic Chain-of-Rotators (CCOR) equation of state for mixtures has been developed and tested on 42 sets of low-pressure and high-pressure binary VLE data (mostly polar systems). When compared to the conventional quadratic mixing rule, this version showed significant improvements in data fitting and an appreciably extended application range. When applied to low-pressure strongly polar systems, this new version gives, in general, better fit of VLE data as compared to the activity-coefficient approach-the popular Hayden-O Connell-Wilson model.