CIESC Journal

• RESEARCH PAPERS • 上一篇    下一篇

肿胀床中蛋白质吸附性能

胡洪波; 姚善泾; 林东强; 朱自强   

  1. Department of Chemical Engineering, Zhejiang University, Hangzhou 310027,China
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2000-09-28 发布日期:2000-09-28
  • 通讯作者: 胡洪波

Adsorption of Protein in the Expanded Bed

HU Hongbo; YAO Shanjing; LIN Dongqiang; ZHU Ziqiang   

  1. Department of Chemical Engineering, Zhejiang University, Hangzhou 310027,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2000-09-28 Published:2000-09-28
  • Contact: HU Hongbo

摘要: The influence of operation parameters on the adsorption performance of protein (bovin serum
albumin, BSA) in an expanded bed was studied using Streamline diethyl aminoethyl (DEAE).
The result of residence time distributions (RTD) and breakthrough curves showed that
adsorption performance of the expanded bed could not be improved by increasing the flow
velocity at the range from 16 ml·min-1 to 26 ml.min-1. The increase of protein
concentration from 0.5 mg·m1-1 to 2 mg.m1-1 resulted in poor adsorption performance. With
increasing temperature from 5℃ to 30℃ and the sedimented bed height from 11.5cm to
22.5cm, the adsorption characteristics in the expanded bed were improved.

关键词: adsorption performance;expanded bed;residence time distribution;breakthrough curve; protein

Abstract: The influence of operation parameters on the adsorption performance of protein (bovin serum
albumin, BSA) in an expanded bed was studied using Streamline diethyl aminoethyl (DEAE).
The result of residence time distributions (RTD) and breakthrough curves showed that
adsorption performance of the expanded bed could not be improved by increasing the flow
velocity at the range from 16 ml·min-1 to 26 ml.min-1. The increase of protein
concentration from 0.5 mg·m1-1 to 2 mg.m1-1 resulted in poor adsorption performance. With
increasing temperature from 5℃ to 30℃ and the sedimented bed height from 11.5cm to
22.5cm, the adsorption characteristics in the expanded bed were improved.

Key words: adsorption performance, expanded bed, residence time distribution, breakthrough curve, protein