Abstract: Due to the concurrence of carbonylation of methanol and hydrogenolysis of methyl formate(MeF)in a slurry reactor,methanol synthesis via MeF has the following advantages:low reaction temperature,high per pass conversion,good heat transfer and direct utilization of crude methanol product as fuel,thus it is a more efficient and more economic methanol production process than the conventional methanol process.In this presentation,a model of the low temperature methanol systhesis(LTMS)via MeF in a bubble column slurry reactor(BCSR)is presented.The model assumes:the gas phase being in plug flow and unmixed slurry phase,catalyst concentration distribution is described by the sedimentation-dispersion model.Liu’s non- linear reaction kinetic expression for LTMS over G-89 catalyst is used in the present model.The effect of various operating variants which include temperature,pressure,superficial gas velocity and catalyst concentration on the reactor productivity are studied.Computation results show that the higher the reaction temperature,the higher the equilibrium conversion and productivity of methanol.Increasing the gas superficial velocity leads to a gradual drop in syngas conversion,while STY goes through a maximum.Under slurry operation condition,high catalyst concentration increases the viscosity of slurry which tends to form large bubbles and,in return,also decreases gas-liquid interfacial area and the residence time of gaseous components in reactor,which affects the efficiency of reactor.