关键词: 分子印迹技术, 固相萃取, 分离技术

Abstract: Molecular imprinting technology (MIT) with predetermination, specific recognition and practicability is widely used in the domain of biosensor, membrane and isomer separation, antibody mimics, enzyme-mimic catalyst and solid phase extraction (SPE).SPE is a better，more simple and more convenient separation technology than liquid-liquid extraction,and has developed rapidly in recent three decades.It is a hopeful domain that uses molecularly imprinted polymers as solid phase extraction packing (MISPE).In this paper, a brief introduction is given about the origin, principle and methods of molecular imprinting technology and solid phase extraction.MISPE for the purpose of environmental sample analysis, medicine separation, pharmaceutical analysis, clinical inspection, and others is emphasized.The achievement, existent problem and trend of MISPE are also reviewed.76 references are cited.

Key words: 分子印迹技术, 固相萃取, 分离技术