Abstract: In this paper,based on the analysis of the characteristics of gas explosion overpressure in pipe,the ME model is used to predict the overpressure in pipe.The ME model is revised on the basis of the law of conservation of energy and the resembling law of explosion energy to eliminate the error caused by using the original ME model to evaluate gas explosion overpressure in pipe.Then combined with the explosion blast reflecting theory the calculation methods of gas explosion overpressure in one end closed pipe are presented.In order to verify the revised ME model, calculated data are compared with experiment data and the data simulated with CFD software.Cylindrical and square experimental tubes are used.The diameter of the cylindrical tube is 2 m,and the width of the square tube is 80 mm.When carrying out the experiments, firstly some types of pressure sensors are installed at different places of the tube.Then methane mixed with air is filled in the tube.Explosion overpressure can be measured with the data acquisition and analyzing system.The simulated tunnel is square which is 1.77 m wide and 30 m long.The tunnel is closed in one end and open in the other. The concentration of methane in the tunnel is 8.5%.The filling length of methane is 6 m.The results show that the calculated data coincide with experiment data and that there is good agreement between the calculated data and simulated data.The calculation methods can be used for risk analysis and assessment of flammable gas explosion accidents in pipe.It can also provide important reference for the design of explosion relief venting and safety measures against the effects of gas explosion in pipe.