盐酸大观霉素溶析结晶过程模拟与分析

CIESC Journal

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盐酸大观霉素溶析结晶过程模拟与分析

鲍颖^a,b; 王静康^a; 王永莉^a

^aSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
^b Post-Doctoral Station of Tianjin Economicand Technological Development Area, Tianjin 300457, China

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2005-04-28 发布日期:2005-04-28
通讯作者: 鲍颖

Simulation Analysis of Dilution Crystallization of Spectinomycin Dihydrochloride Pentahydrate

BAO Ying^a,b; WANG Jingkang^a; WANG Yongli^a

^aSchool of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
^b Post-Doctoral Station of Tianjin Economicand Technological Development Area, Tianjin 300457, China

Received:1900-01-01 Revised:1900-01-01 Online:2005-04-28 Published:2005-04-28
Contact: BAO Ying

摘要/Abstract

摘要： A mathematical model for dilution crystallization of spectinomycin dihydrochloride pentahydrate was established on the basis of the population and mass balance. Three operating modes, i.e., constant mass rate addition of diluent, constant mass fraction of diluent and constant size-independent growth rate, were investigated over a wide range of controlled parameters. The intrinsic characteristics of the crystallization process and the influence of operation parameters were analyzed in detail. Suitable strategy for better performance was suggested.

关键词: 模拟分析技术;稀释法;结晶化行为;奇霉素;二盐酸化物

Abstract: A mathematical model for dilution crystallization of spectinomycin dihydrochloride pentahydrate was established on the basis of the population and mass balance. Three operating modes, i.e., constant mass rate addition of diluent, constant mass fraction of diluent and constant size-independent growth rate, were investigated over a wide range of controlled parameters. The intrinsic characteristics of the crystallization process and the influence of operation parameters were analyzed in detail. Suitable strategy for better performance was suggested.

Key words: spectinomycin dihydrochloride pentahydrate, dilution crystallization, mathematical model

鲍颖,王静康,王永莉. 盐酸大观霉素溶析结晶过程模拟与分析[J]. CIESC Journal.

BAO Ying, WANG Jingkang, WANG Yongli. Simulation Analysis of Dilution Crystallization of Spectinomycin Dihydrochloride Pentahydrate[J]. .

盐酸大观霉素溶析结晶过程模拟与分析

Simulation Analysis of Dilution Crystallization of Spectinomycin Dihydrochloride Pentahydrate

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