Abstract: Today, a significant environmental problem in China is the municipal and industrial landfills, which can release toxic compounds, such as all kinds of organic pollutants together with heavy metals, into the environment. Landfill leachate is a sort of organic refractory effluent with high concentration and complex pollutant constituents. In order to treat this kind of wastewater efficiently, it is indispensable to analyze the complex constituents in landfill leachate.The inductively coupled plasma-mass spectrometry method (ICP-MS) and gas chromatograph-mass spectrometer method(GC-MS) were used to measure the concentration of heavy metals and organic pollutants in the landfill leachate generated from Datianshan landfill site in Guangzhou.In this kind of landfill leachate, 87 kinds of organic pollutants were discovered, 16 kinds of which belong to the list of environmental priority pollutants according to US EPA.Furthermore, hydrocarbon compounds accounted for about 52% among all these kinds of organic pollutants.In addition, 46 kinds of heavy metals in this kind of leachate were detected. Among them, 10 kinds of heavy metals belong to the list of environmental priority pollutants. In those priority pollutants for heavy metals, the concentration of Cr, Ni, Zn, Cu and Pb were higher than others, especially Cr and Zn, which were more than 100 μg•L^-1.