Abstract: The concept of interfacial non-equilibrium during mass transfer between gas and liquid was presented to explain the mechanism of interfacial mass transfer in which the driving force of gas-liquid interphase mass transfer was considered coming from the non-equilibrium.Based on the general chemical potential driving force equation, a concentration corrrelation between two phases at interface was derived and solved at different bulk liquid concentrations in the absorption process.The computational results showed that the interfacial concentration of absorbed component on the liquid side was strongly affected by a dimensionless number Yo and was also dependent on bulk concentration.The CO₂ interfacial concentration on the liquid side in stationary absorption by pure methanol, ethanol and n-propanol absorbent respectively were measured by using micro laser holographic interference technique to validate the model proposed.The experimental values were in good agreement with the calculated ones.