Abstract: The method for the preparation of methylcyclohexanone and methylcyclohexanol via selective aerobic oxidation of methylcyclohexane catalyzed by metalloporphyrin was reported for the first time.Catalyzed by Mn(Ⅲ) porphyrin, methylcyclohexane could be oxidized by air.The products were three isomers of methylcyclohexanone, 1-methylcyclohexanol and 2-methylcyclohexanol. The effect on the conversion and selectivity was investigated when reaction conditions or porphyrin structure were changed.With the alkoxyl substituting metalloporphyrins as catalysts,the selectivity of methylcyclohexanone and methylcyclohexanol was better than using TPPMnOAc.Moreover, the larger the substitute’s volume, the higher the conversion, and selectivity still remained satisfactory.Using 5,10,15,20-tetra(para-heptaneoxylphenyl) porphyrin manganese as catalyst, the conversion was up to 20% and the overall selectivity of methylcyclohexanone and methylcyclohexanol was 76%.