Abstract: Experimental results indicated that the resin of 4-aminopyridine (4-APR) showed good ability to adsorb Mo(Ⅵ) at pH=4.1 in the HAc-NaAc medium.The statically saturated sorption capacity was 594 mg Mo(Ⅵ)•(g resin)^-1，Mo(Ⅵ) adsorbed on 4-APR could be eluted by 3 mol•L^-1 HCl or 3 mol•L^-1 NaOH quantitatively. The sorption rate constants determined at various temperatures were respectively k15℃=2.24×10^-5s^-1,k_25℃=3.30×10^-5s^-1,k_35℃=4.79×10^-5s^-1,and k_45℃=6.85×10^-5s^-1.The sorption apparent activation energy Ea was 29.1 kJ•mol^-1.The sorption mechanism showed that the nitrogen atoms of the functional group of 4-APR coordinated with Mo(Ⅵ) to form coordination bonds,and the coordination molar ratio of ［4-AP］ to Mo(Ⅵ) was 1∶2.