CIESC Journal

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离子液体在生物催化制备手性化合物中的应用

杨忠华,曾 嵘,吕早生,王光辉,伍 林,姚善泾
  

  1. 武汉科技大学化学工程与技术学院;湖北大学化学与化工学院;浙江大学化学工程与生物工程学系
  • 出版日期:2010-07-28 发布日期:2010-07-29

New development of ionic liquids and their application in chiral synthesis with biocatalysis

YANG Zhonghua,ZENG Rong,LÜ Zaosheng,WANG Guanghui,WU Lin,YAO Shanjing   

  1. College of Chemical Engineering,Resources and Environment,Wuhan University of Science and Technology; Faculty of Chemistry and Chemical Engineering,Hubei University; Department of Chemical and Biochemical Engineering,Zhejiang University
  • Online:2010-07-28 Published:2010-07-29

摘要: 介绍了离子液体的特性;同时对近几年报道的离子液体对酶及细胞活性影响的研究进行了归纳、总结和分析;详细介绍了近几年报道的有关离子液体在生物催化手性化合物合成中的应用情况,特别是对于水解酶和氧化还原酶催化的反应按反应的类型分别进行了归纳和分析。

Abstract: The characteristics of ionic liquids are reviewed. The toxicity of ionic liquids to enzymes and living cells reported in recent years is also summarized and analyzed. Especially, the recent development of their application in chiral synthesis by biocatalysis with hydrolases and oxidoreductases is presented.