CIESC Journal

• SEPARATION SCIENCE & ENGINEERING • 上一篇    下一篇

微波辅助胶团提取甘草中的甘草酸和甘草甙

孙晨; 谢渝春; 刘会洲   

  1. a Chemistry and Chemical Engineering Department, Graduate University of Chinese Academy of
    Sciences, Beijing 100049, China
    b Laboratory of Separation Science and Engineering, State Key Laboratory of Biochemical
    Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100080,
    China
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-08-28 发布日期:2007-08-28
  • 通讯作者: 孙晨

Microwave-assisted micellar extraction and determination of glycyrrhizic acid and
liquiritin in licorice root by HPLC

SUN Chen; XIE Yuchun; LIU Huizhou   

  1. a Chemistry and Chemical Engineering Department, Graduate University of Chinese Academy of
    Sciences, Beijing 100049, China
    b Laboratory of Separation Science and Engineering, State Key Laboratory of Biochemical
    Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100080,
    China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-08-28 Published:2007-08-28
  • Contact: SUN Chen

摘要: The feasibility of employing non-ionic surfactant (Triton X-100) as an alternative and
effective solvent for the microwave-assisted extraction of glycyrrhizic acid (GA) and
liquiritin (LQ) from licorice root was studied. The optimal extraction parameters based on
the microwave-assisted micellar extraction technique were determined. Under the optimal
conditions, i.e. 5% (by volume) Triton X-100, microwave-assisted extraction for 3—5min at
373K, the percentage extraction of active ingredients reached the highest value. The
preconcentration factor for GA and LQ (about 13.5) and the extraction efficiency for these
two ingredients approached 100% showed the coupling of microwave-assisted extraction and
cloud-point extraction could be employed as a new and effective technique for the rapid
extraction and preconcentration of pharmacologically active ingredients from medicinal
plants such as licorice root without disturbing chromatographic analysis.

关键词: microwave-assisted micellar extraction;cloud-point extraction;Triton X-100;glycyrrhizic acid;liquiritin

Abstract: The feasibility of employing non-ionic surfactant (Triton X-100) as an alternative and
effective solvent for the microwave-assisted extraction of glycyrrhizic acid (GA) and
liquiritin (LQ) from licorice root was studied. The optimal extraction parameters based on
the microwave-assisted micellar extraction technique were determined. Under the optimal
conditions, i.e. 5% (by volume) Triton X-100, microwave-assisted extraction for 3—5min at
373K, the percentage extraction of active ingredients reached the highest value. The
preconcentration factor for GA and LQ (about 13.5) and the extraction efficiency for these
two ingredients approached 100% showed the coupling of microwave-assisted extraction and
cloud-point extraction could be employed as a new and effective technique for the rapid
extraction and preconcentration of pharmacologically active ingredients from medicinal
plants such as licorice root without disturbing chromatographic analysis.

Key words: microwave-assisted micellar extraction, cloud-point extraction, Triton X-100, glycyrrhizic acid, liquiritin