Abstract: The solvent extraction method was used to obtain trans-1,2-cyclohexanediol in the synthesis from cyclohexene and hydrogen peroxide. On the basis of the phase equilibrium for trans-1,2-cyclohehanediol in methyl acetate, by using the laser monitoring technique, the solubilities of trans-1,2-cyclohexanediol in methyl acetate and water mixed solvent were measured in a larger temperature interval. A solubility UNIFAC model was proposed. The model was verified with experimental data in ternary systems of water+methyl acetate+trans-1,2-cyclohexanediol, and the solubilities calculated with the model were in good agreement with experimental data.