Abstract: Synthesis of tributyl citrate using macroporous strong acid cationic exchange resin as a nonhomogeneous catalyst was investigated，the optimum reaction parameters were found as：citric acid to butanol molar ratio of 1∶4.5，catalyst amount of 20% citric acid mass，reaction temperature of 130℃，under which the esterification yield was above 94.3%. The reaction product purification was also investigated and the purity of purified tributyl citrate was higher than 99.5%.