CIESC Journal
• 材料化学工程与纳米技术 • 上一篇 下一篇
马威,刘勇,张淑芬
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MA Wei, LIU Yong, ZHANG Shufen
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摘要:
2-(2-羟基-5-甲基苯基)-2H-苯并三唑(UV-P)经过羟基乙酰化、N-溴代丁二酰亚胺(NBS)溴代,合成了具有高反应活性的2-(2-乙酰氧基-5-溴甲基苯基 Abstract: 2-(2-Acetoxy-5-bromomethylphenyl)-2H-benzotriazole with high reactivity was synthesized by two steps: acetylation of hydroxyl group of 2-(2-hydroxy-5-methylphenyl)-2H-benzotriazole(UV-P)and bromination of acetylated UV-P with N-bromosuccinimide(NBS).Effects of reaction conditions including solvent, initiator, temperature, reaction time, ratio of the reactants and concentration of acetylated UV-P on the yield of the target product and reaction efficiency were studied. The yield reached 60% under the following optimum conditions: under N2 atmosphere, CCl4 as solvent and 2-2-azo-bis-isbutyronitrile (AIBN) as initiator, with 1∶1 for the molar ratio of NBS to 2-(2-acetoxy-5-methylphenyl)-2H-benzotriazole, and bromination under reflux for 1h. The structure of the product was confirmed by IR, 1H NMR and MS spectroscopies. 引用本文 马威,刘勇,张淑芬. 2-(2-乙酰氧基-5-溴甲基苯基)-2H-苯并三唑的合成 [J]. CIESC Journal. MA Wei, LIU Yong, ZHANG Shufen. Synthesis of 2-(2-acetoxy-5-bromomethylphenyl)-2H-benzotriazole[J]. . 使用本文 0 / / 推荐 导出引用管理器 EndNote|Ris|BibTeX 链接本文: https://hgxb.cip.com.cn/CN/ https://hgxb.cip.com.cn/CN/Y2010/V61/I11/2992
Abstract:
2-(2-Acetoxy-5-bromomethylphenyl)-2H-benzotriazole with high reactivity was synthesized by two steps: acetylation of hydroxyl group of 2-(2-hydroxy-5-methylphenyl)-2H-benzotriazole(UV-P)and bromination of acetylated UV-P with N-bromosuccinimide(NBS).Effects of reaction conditions including solvent, initiator, temperature, reaction time, ratio of the reactants and concentration of acetylated UV-P on the yield of the target product and reaction efficiency were studied. The yield reached 60% under the following optimum conditions: under N2 atmosphere, CCl4 as solvent and 2-2-azo-bis-isbutyronitrile (AIBN) as initiator, with 1∶1 for the molar ratio of NBS to 2-(2-acetoxy-5-methylphenyl)-2H-benzotriazole, and bromination under reflux for 1h. The structure of the product was confirmed by IR, 1H NMR and MS spectroscopies.
马威,刘勇,张淑芬. 2-(2-乙酰氧基-5-溴甲基苯基)-2H-苯并三唑的合成 [J]. CIESC Journal.
MA Wei, LIU Yong, ZHANG Shufen. Synthesis of 2-(2-acetoxy-5-bromomethylphenyl)-2H-benzotriazole[J]. .
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链接本文: https://hgxb.cip.com.cn/CN/
https://hgxb.cip.com.cn/CN/Y2010/V61/I11/2992