关键词: 溶解度模型, 超临界体系, 固体溶质, 夹带剂

Abstract: Based on the study on the Sovova model with good correlation precision in literature and the MST-T&G model as the reference model，a modified MST-T&G model (M-MST-T&G model) was proposed by considering the relationship between the solubilities of supercritical binary and ternary systems. In this new model，the solubility functions in supercritical binary and ternary systems were chosen as the framework. The calculation accuracy of the new model was verified by 1195 groups of solubility data of 13 solutes (including heterocyclic aromatic hydrocarbons，aliphatic acids，dye chemicals and pharmaceutical chemicals) in supercritical carbon dioxide with 10 co-solvents (including alcohols，ketones and alkanes). Besides，the accuracy of the new model was compared with that of the traditional MST-T&G model. The new model obtained better correlation with average absolute relative deviation reaching 9.63% and relative deviation scaled down by 32.30% compared with the traditional MST-T&G model.

Key words: solubility model, supercritical system, solid solute, co-solvent