Abstract: Simulation computation shows that the performance of a flow reversal reactor depends weakly on the heat transfer parameters but strongly on the global kinetic parameters involved in its transient model. Based on fitting the model prediction of operation performance with the results obtained in bench - scale test, the global kinetic parameters in observed reaction rate equation are modified.Performance prediction and parameter analysis of one - stage flow reversal reactor for SO2 oxidation reaction are completed by using the transient heterogeneous model developed and the parameters modified. Recommendations for designing, operating and optimizing this reactor configuration are given.