Abstract: Physical properties, such as dynamic viscosity, saturated vapor pressure, specific heat capacity, dissolution enthalpy, enthalpy of vaporization and standard gaseous enthalpy of formation for oxyfluorfen and its synthetic intermediates, were determined or calculated. The intermediates include 4 - chlorobenzotriflouride, 3,4- dichlorobenzotriflouride, 1, 3 - bis ( 2 - chloro - 4 - trifluomethyl phenoxy) benzene and 2,4 - bis(2 - chloro - 4 - trifluomethyl phenoxy) nitrobenzene. Tne quantum mechanics molecular models (AMI) and the application of group contribution method based on molecular structure were verified. The results have not been reported in the literature, and could provide chemical engineering design with fundamental data.