Abstract: Drug delivery systems (DDS) have been developed as a new means of releasing drugs with accurate dosage and convenient administration.It will be promising in clinical application with high effectiveness and safety of drugs, and high compliance of patients.In this review, the status quo and progress of main non-injection routes (oral,trans-dermal and mucosal DDS) are summarized.The application of novel technologies such as targeting, cell micro-encapsulation and micro-fabrication in DDS is introduced.Finally, the problems and some strategy to resolve such problems are addressed.

Key words: 药物释放系统, 靶向, 细胞微囊化, 微加工

摘要： 介绍了口服、透皮、黏膜等非注射给药途径药物释放系统的研究进展，以及靶向、细胞微囊化和微加工等新技术手段在药物释放系统中的应用，评述了药物释放系统的问题及解决手段.

关键词: 药物释放系统, 靶向, 细胞微囊化, 微加工