Abstract:

Direct and indirect ozonation of p-toluene sulfonic acid(p-TSA), a typical pollutant in pharmaceutical wastewater, was studied.The results showed that at the conditions of pH 2—13, ozone flow rate 16—64 mg·min^-1 and pollutant concentration 100—5000 mg·L^-1, the degradation followed the pseudo-first-order kinetics.The higher pH and ozone flow rate, and lower concentration were, the larger reaction constants.In order to consider the relative contribution of direct and indirect oxidation a kinetic model of ozonation was set up, in which 3 k_HO2-·/k₀ was selected as kinetic parameter.The effect of pH, ozone flow rate and pollutant concentration on 3 k_HO2-·/k₀ was analyzed quantitatively, which could provide fundamental data for the application of ozonation in pharmaceutical wastewater pollution control.

Key words: 制药中间体, 对甲基苯磺酸, 臭氧, 动力学

摘要：

选用典型制药中间体对甲基苯磺酸(p-TSA)作为模型污染物，研究了臭氧氧化技术对p-TSA的直接氧化和间接氧化效果。结果表明，在pH为2～13、臭氧流量16～64 mg·min^-1和污染物浓度100～5000 mg·L^-1条件下，臭氧氧化p-TSA均符合拟一级动力学降解规律，且pH、臭氧投加量的增大都有利于拟一级动力学常数的提高，而初始污染物浓度的提高则抑制拟一级动力学常数的增大。建立了表征臭氧氧化过程中直接反应和间接反应各相对贡献率的动力学模型，定量研究了臭氧流量、

关键词: 制药中间体, 对甲基苯磺酸, 臭氧, 动力学