摘要：

Preparation and properties of solid lipid nanoparticles carried octyl methoxycinnamate(OMC）were studiedThe influence of octyl methoxycinnamate（OMC）and pH value on the distribution, size, Zeta potential of solid lipid nanoparticle were studiedMeanwhile the configuration, particle size, composition and sunscreen properties were characterizedThe result showed that the Zeta potential of solid lipid nanoparticle was about 40 mV with optimizing composition and middle or weak basic pH condition The average particle size of solid lipid nanoparticle was about 150 nm and the particle distribution was homogeneousParticle configuration was spherical with or without OMC and little flocculationCarried OMC increased the particle sizeOMC with lipid material, emulsifier formed the solid lipid nanoparticle together but not carried in the coreThe solid lipid nanoparticle with OMC have good ultraviolet adsorption and the synergy function was between the solid lipid nanoparticles and sunscreen.