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CRYSTALLIZATION PROCESS OF PHENYLPYRUVIC ACID SODIUM SALT

Fan Weiping;Wu Yue;Ouyang Pingkai;Zhu Jianliang(Department of Biotechnology and Bioengineering,Nanjing University of Chemical Technology,Nanjing 210009)   

  • Online:1998-02-25 Published:1998-02-25

苯丙酮酸钠盐结晶过程

范伟平,吴月,欧阳平凯,朱建良   

  1. 南京化工大学生物工程与科学系!南京210009,南京化工大学生物工程与科学系!南京210009,南京化工大学生物工程与科学系!南京210009,南京化工大学生物工程与科学系!南京210009

Abstract: The mixing-precipitation process for producing phenylpyruvic acid sodium salt(PPNa) by neutralization of phenylpyruic acid(PPA) with aqueous sodium hydroxide in a semi-batch stirred tank was studied.The effects of mixing characteristics and chemical characteristics on the precipitation process were investigated experimentally.It was found that the crystals growth rate and morphology obviously changed due to ripening.Crystal redissolution agglomeration and solvent inclusion also changed the purity of PPNa product considerably.

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