关键词: α-蒎烯, 三乙胺, 乙酸酐, 臭氧化物, 蒎酮酸酯

Abstract: Six pinonic acid esters were synthesized from one-pot ozonolysis reaction using α-pinene and alcohol as raw materials, dichloromethane as solvent, and decomposition of the prepared ozonide by acetic anhydride (AA) with triethylamine (TEA) as catalyst. The influences of acetic anhydride quantity, triethylamine quantity, reaction time and reaction temperature were investigated. The synthesis conditions were optimized by orthogonal experiment. The optimized conditions were as follows：nAA/nα-pinene = 3.0∶1, nTEA/nα-pinene = 0.75∶1, time and temperature 60 min and 30 ℃ respectively. The yields of six pinonic acid esters were above 60%. The structures of the six pinonic acid esters were identified and characterized by IR, 1H NMR, 13C NMR and MS. This method was a convenient and efficient way to synthesize pinonic acid esters, which had such advantages as simple operation, mild conditions and high yields.

Key words: α-pinene, triethylamine, acetic anhydride, ozonide, pinonic acid esters