Abstract: The disruption kinetics of a microbial cell was studied by using a horizontal bead mill (Dyno -mill). A mechanism was put forward on the basis of experimental results and prior work. It was composed of the release of intracellular products,and their solubilization and inactivation during the cell disruption process. A new model of disruption kinetics was established, which was used to regress the experimental data and calculate the relevant parameters. The new kinetics equation could better explain the deactivation phenomena of intracellular products.

摘要： 在实验和前人研究的基础上,对微生物细胞珠磨破碎动力学进行了分析,提出细胞破碎过程中存在胞内产物释放、溶解和失活机理,据此建立了新的动力学模型,并对实验数据进行了回归,计算出有关参数。新的动力学方程能较好地解释产物失活现象。