Abstract: Inverse suspension polymerization of acrylamide was carried out in benzene continuous phase using cellulose acetate as suspension stabilizer and ammonium persulfate as initiator.An ideal recipe was recommended for the preparation of monodispersed polyacrylamide particles of 150—297μm in diameter and 1.5—4.0 nm in polymer network pore size through experiments.The effects of initial monomer concentration,stabilizer concentration,initiator concentration and agitation rate on the diameter and diameter distribution of polymer particles were systematically studied.