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MEASUREMENT AND CORRELATION OF TAXOL SOLUBILITY IN METHANOL,ETHANOL AND METHANOL-WATER SYSTEMS

HAN Jinyu,XIAO Jian,WANG Hua,CHANG Heying and MA Peisheng (School of Chemical Engineering and Technology, Tianjin University,Tianjin?300072,China)   

  • Online:2001-01-25 Published:2001-01-25

紫杉醇溶解度的测定与关联

韩金玉,肖剑,王华,常贺英,马沛生   

  1. 天津大学化工学院!天津300072,天津大学化工学院!天津300072,天津大学化工学院!天津300072,天津大学化工学院!天津300072,天津大学化工学院!天津300072

Abstract: Taxol is a unique antitumor drug that appears to exert its activity as a result of interference with microtubular structure and function. The Taxol solubility of in methanol, ethanol and methanol-water was measured by the equilibrium method in this paper. The data obtained were correlated by the regress equation and ANN model. The results showed that the both were in excellent agreement with the experimental data and the ANN model was more convenient than the regress equation.

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