Abstract: The general mathematical model for batch cooling crystallization was established based on
the popula tion balance equation considering the change of slurry volume, and simulated
with crystallization thermodynamics, kinetics and mass balance employing bed voidage. In
the system of vitamin C-water-ethanol, reliability of this model was verified by comparison
between simulation results and experimental data. The effects of operation parameters on
product quality can be systematically investigated by modeling simulation.

Key words: batch cooling crystallization, modeling simulation, vitamin C

摘要： The general mathematical model for batch cooling crystallization was established based on
the popula tion balance equation considering the change of slurry volume, and simulated
with crystallization thermodynamics, kinetics and mass balance employing bed voidage. In
the system of vitamin C-water-ethanol, reliability of this model was verified by comparison
between simulation results and experimental data. The effects of operation parameters on
product quality can be systematically investigated by modeling simulation.

关键词: batch cooling crystallization;modeling simulation;vitamin C