BIOCATALYSIS-COUPLED CELL GROWTH PROCESS IN 1，3-PROPANEDIOL PRODUCTION BY Klebsiella pneumoniae

Abstract

Abstract: This paper focuses on the research of the bioconversion of 1,3-propanediol by Klebsiella pneumoniae. The linear correlation of cell growth and 1,3-propanediol synthesis was found. An equation of the relationship between cell growth and biocatalysis was given.With the analysis of metabolism, it was discovered that the cell regulated the NADH production by cell growth in order to supply enough reductive equivalent for enzyme catalysis. A conclusion was drawn that the cell growth was coupled with the reactivation of a key-enzyme which catalyzes 1,3-propanediol production in Klebsiella pneumoniae.

Key words: 生长与催化耦联, Klebsiella pneumoniae, 1,3-丙二醇, 甘油

关键词: 生长与催化耦联, Klebsiella pneumoniae, 1,3-丙二醇, 甘油

DU Chenyu, LI Chun, YANG Dong, ZHANG Yanping, CAO Zhu’an. BIOCATALYSIS-COUPLED CELL GROWTH PROCESS IN 1，3-PROPANEDIOL PRODUCTION BY Klebsiella pneumoniae[J]. CIESC Journal, 2004, 55(3): 505-508.

杜晨宇, 李春, 杨东, 张延平, 曹竹安. Klebsiella pneumoniae合成1,3-丙二醇过程中的生长与催化耦联 [J]. 化工学报, 2004, 55(3): 505-508.

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BIOCATALYSIS-COUPLED CELL GROWTH PROCESS IN 1，3-PROPANEDIOL PRODUCTION BY Klebsiella pneumoniae

Klebsiella pneumoniae合成1,3-丙二醇过程中的生长与催化耦联

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