Abstract: The nitrosation of cyclohexanecarboxylic acid (CCA) with nitrosyl sulfuric acid is an important industrial process to produce ε-caprolactam. The experiments showed that there also existed a parallel reaction between CCA and SO₃ as well as an intercrossing reaction between caprolactam and nitrosyl sulfuric acid,except for the nitrosation of CCA. A reaction kinetics model of the process was proposed, and the model parameters were indirectly determined by the results from the analysis-synthesis experimental design assuming the reactions in the nitrosation system having no influence on each other.This model not only could explain the control parameters in the industrial process,but also could support the optimization of the industrial process.

Key words: 己内酰胺, 环己烷羧酸, 亚硝基硫酸, 亚硝化, 反应动力学

摘要： 由环己烷羧酸与亚硝基硫酸的亚硝化反应制取己内酰胺是一个重要的工业反应过程.实验证实了该过程伴有环己烷羧酸与三氧化硫作用的平行副反应以及己内酰胺与亚硝基硫酸作用的串联副反应，由此提出了亚硝化过程的反应动力学模型.在假定各主、副反应之间没有交互影响的基础上，通过分析-综合实验方法间接地确定了模型参数.该模型能够很好地解释工业亚硝化过程的控制参数，并为工业亚硝化过程的进一步优化提供了理论依据.

关键词: 己内酰胺, 环己烷羧酸, 亚硝基硫酸, 亚硝化, 反应动力学