Abstract:

In this paper, calcium alginate gel beads were prepared through a homemade microcapsule preparation system with multi-nozzles under forced high-voltage electrostatic field.The effect of operation parameters on the large-scale preparation of gel beads was analyzed.The results showed that the air pressure of feed was the decisive factor affecting the size and yield of gel beads, and the size distribution was dependent on several factors including the distribution of electric field, pulse potential, air pressure of feed, pulse frequency, pulse width and threshold potential.The gel beads with good sphericity, smooth surface and low dispersivity (CV<20%) can be prepared by adjusting and optimizing above parameters.It is more important that the yield of gel beads by the microcapsule preparation system is 20—40 folds higher than the traditional electrostatic droplet generator, which makes it possible to realize the large-scale preparation of gel beads.

Key words:

微胶囊制备系统, 高压静电, 海藻酸钠, 微胶珠, 规模化制备

摘要： 利用自制多通道强制电场微胶囊制备系统制备海藻酸钙微胶珠，分析了微胶囊制备系统中电极电场分布规律，考察了进料气压、脉冲电压、脉冲频率、脉冲宽度、辅助电压等系统调节参数对微胶珠制备过程的影响，发现制备过程中微胶珠粒径大小与产率主要由进料气压决定，而微胶珠的分散性则是由多个因素共同作用的结果。通过优化条件制备的微胶珠分散系数较小（CV<20%），球形度良好，表面光洁，并且产率是传统静电法的20~40倍，使海藻酸钙微胶珠大规模制备成为可能。

关键词:

微胶囊制备系统, 高压静电, 海藻酸钠, 微胶珠, 规模化制备