Abstract:

2-(2-Acetoxy-5-bromomethylphenyl)-2H-benzotriazole with high reactivity was synthesized by two steps: acetylation of hydroxyl group of 2-(2-hydroxy-5-methylphenyl)-2H-benzotriazole(UV-P)and bromination of acetylated UV-P with N-bromosuccinimide(NBS).Effects of reaction conditions including solvent, initiator, temperature, reaction time, ratio of the reactants and concentration of acetylated UV-P on the yield of the target product and reaction efficiency were studied. The yield reached 60% under the following optimum conditions: under N₂ atmosphere, CCl₄ as solvent and 2-2-azo-bis-isbutyronitrile (AIBN) as initiator, with 1∶1 for the molar ratio of NBS to 2-(2-acetoxy-5-methylphenyl)-2H-benzotriazole, and bromination under reflux for 1h. The structure of the product was confirmed by IR, ¹H NMR and MS spectroscopies.

摘要：

2-(2-羟基-5-甲基苯基)-2H-苯并三唑（UV-P）经过羟基乙酰化、N-溴代丁二酰亚胺（NBS）溴代，合成了具有高反应活性的2-(2-乙酰氧基-5-溴甲基苯基