Abstract:

The proposition and development of the newly emerging nano-cryopreservation of biological materials are reviewed and summarized. Attentions are focused on the elucidation of the freezing response of biological materials with nano-particle solution，the effects of nano-particles on cryo-protectants and the nucleation mechanism of nano-particle solution. Technical strategies through introduction of nan-particles to efficiently improve the function of cryo-protectant are interpreted. The latest research status in the field is analyzed. Future directions worthy of pursuing are discussed.

摘要：

对新兴的生物材料纳米低温冻存技术的提出、发展做了回顾和总结，重点阐述了纳米颗粒溶液与生物组织的低温响应、纳米颗粒对低温保护剂性能的影响以及纳米颗粒溶液成核相变机理等问题，解读了纳米颗粒用于改善低温保护剂性能的技术途径，剖析了当前该领域的研究现状，并讨论了进一步的发展方向。