Chin.J.Chem.Eng. ›› 2012, Vol. 20 ›› Issue (4): 673-678.

• SEPARATION SCIENCE AND ENGINEERING • Previous Articles     Next Articles

Separation of α-tocopherol with a two-feed simulated moving bed

WEI Feng; SHEN Bo; CHEN Mingjie; ZHOU Xianbo; ZHAO Yingxian   

  1. Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China
  • Received:2011-03-22 Revised:2011-06-09 Online:2011-06-09 Published:2012-08-28

双进料模拟移动床分离α-生育酚

危凤; 沈波; 陈明杰; 周先波; 赵迎宪   

  1. Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China

Abstract: A two-feed simulated moving bed (SMB) was proposed to utilize the stationary phase more effectively. Zone I is disconnected with zone II and zone III is disconnected with zone IV. Two feeds are added to zones I and III, while two desorbents are added to zones II and IV separately. The investigation on the movement of concentration bands indicated that the tail of the strong retained solute and the front of the weak retained solute were eluted from zones I and III orderly, so the streams from zones I and III could be cut into different fractions to give the products with high purity. The two-feed SMB was used to separate α-tocopherol from its homologue mixture successfully, and could double the productivity if both feeds were identical to the feed in the conventional four-zone SMB. The solvent consumption could be reduced by reusing the middle fraction without solutes.

Key words: simulated moving bed, two-feed, tocopherol

摘要: A two-feed simulated moving bed (SMB) was proposed to utilize the stationary phase more effectively. Zone I is disconnected with zone II and zone III is disconnected with zone IV. Two feeds are added to zones I and III, while two desorbents are added to zones II and IV separately. The investigation on the movement of concentration bands indicated that the tail of the strong retained solute and the front of the weak retained solute were eluted from zones I and III orderly, so the streams from zones I and III could be cut into different fractions to give the products with high purity. The two-feed SMB was used to separate α-tocopherol from its homologue mixture successfully, and could double the productivity if both feeds were identical to the feed in the conventional four-zone SMB. The solvent consumption could be reduced by reusing the middle fraction without solutes.

关键词: simulated moving bed, two-feed, tocopherol