Abstract: In φ30 packing column, the synthesis of isoamyl acetate is studied by using fluidising catalytic reaction rectification, in which the catalyst powder is fluidizing with feed. it has been investigated that catalyst content, acetic acid-alcohol mole ratio, feed positions of acetic acid and isoamyl alcohol, reflux ratio and reflux position of water phase affect on the process. Under the selected experiment conditions, the isoamyl ACetate content of the ether phase at the top of the tower is about 95.11% and the conversion of isoamyl acetate is about 95%.