高纯度辣椒碱提取工艺分析及实验研究

doi:10.3969/j.issn.0438-1157.2013.08.029

化工学报 ›› 2013, Vol. 64 ›› Issue (8): 2907-2912.DOI: 10.3969/j.issn.0438-1157.2013.08.029

高纯度辣椒碱提取工艺分析及实验研究

王金艳^1,2, 王玉琪¹, 范召运¹, 郑岚¹, 倪士峰², 姚瑞清¹, 陈开勋¹, 邵纪生¹

1. 西北大学化工学院, 陕西西安 710069;
2. 西部资源生物与现代生物技术教育部重点实验室, 陕西西安 710069

收稿日期:2012-12-08 修回日期:2013-04-20 出版日期:2013-08-05 发布日期:2013-08-05
通讯作者: 王玉琪
作者简介:王金艳(1988- ),女,硕士研究生。
基金资助:
西部资源生物与现代生物技术教育部重点实验室(西北大学)开放基金项目(ZS12105);陕西省教育厅专项科研计划项目(11JK0598)。

Technological analysis and experimental study on high-purity capsaicin extraction

WANG Jinyan^1,2, WANG Yuqi¹, FAN Zhaoyun¹, ZHENG Lan¹, NI Shifeng², YAO Ruiqing¹, CHEN Kaixun¹, SHAO Jisheng¹

1. School of Chemical Engineering, Northwest University, Xi'an 710069, Shaanxi, China;
2. Key Laboratory of Resource Biology and Biotechnology in Western China, Xi'an 710069, Shaanxi, China

Received:2012-12-08 Revised:2013-04-20 Online:2013-08-05 Published:2013-08-05
Supported by:
supported by the Opening Foundation of Key Laboratory of Resource Biology and Biotechnology in Western China(Northwest University)(ZS12015)and the Ministry of Education and Natural Science Foundation of Education Committee of Shaanxi Province(11JK0598).

摘要/Abstract

摘要： 高纯度辣椒碱在医药、食品等领域有着很大的市场需求。以干辣椒为提取原料,采用多元价值取向模型对现有溶剂法、超临界萃取、溶剂-超临界耦合及溶剂-离子交换耦合4种提取高纯辣椒碱工艺进行了综合评价,评估结果表明溶剂法耦合离子交换法工艺明显优于其他工艺路线,其综合优度为0.8049。在此基础上对最佳的溶剂-离子交换耦合工艺开展了实验研究,得出最优提取工艺参数为:上柱浓度331.4 mg·L^-1,速度18.8 ml·min^-1,pH值5.0,温度为室温,并且得出上柱纯化溶液浓度、流速等相关参数值及作用。制得的产品辣椒碱纯度高达98.42%。

关键词: 多元价值取向模型, 溶剂提取, 离子交换树脂, 纯化, 辣椒碱

Abstract: High purity capsaicin is in great demand in the fields of medicine and food.The multi-element valued model is used to evaluate four capsaicin extraction technologies including solvent extraction,supercritical fluid extraction,coupled solvent-supercritical extraction and coupled solvent-ion exchange route.The results confirm that coupled solvent-ion exchange route is the optimal technological process,preceding other routes obviously.Experimental study on the coupled solvent-ion exchange route shows that the optimum parameters for capsaicin extraction are:initial concentration 331.4 mg·L^-1,flow rate 18.8 ml·min^-1,pH 5.0,and room temperature.The column purification parameters such as the solution concentration and velocity with its effects are also obtained,and the capsaicin purity of final production reaches 98.42%.

Key words: multi-element valued model, solvent extraction, ion exchange resin, purification, capsaicin

中图分类号:

O6-332

王金艳, 王玉琪, 范召运, 郑岚, 倪士峰, 姚瑞清, 陈开勋, 邵纪生. 高纯度辣椒碱提取工艺分析及实验研究[J]. 化工学报, 2013, 64(8): 2907-2912.

WANG Jinyan, WANG Yuqi, FAN Zhaoyun, ZHENG Lan, NI Shifeng, YAO Ruiqing, CHEN Kaixun, SHAO Jisheng. Technological analysis and experimental study on high-purity capsaicin extraction[J]. CIESC Journal, 2013, 64(8): 2907-2912.

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高纯度辣椒碱提取工艺分析及实验研究

Technological analysis and experimental study on high-purity capsaicin extraction

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