Abstract: With an example of a distillation tower,an important equipment in chemical industry,this paper gives an investigation into the multivariable intelligent controller using the neural network which includes the model of the Plant,the multivariable control systems,and the model-free intelligent control algorithm.The simulation results show that such a novel controller is effective to control the complex chemical prncesses.Having good performances,strong robustness to the changes of the process model and simple structure,it can be conveniently used in practical engineering.