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OPTIMAL FEED STRATEGY FOR FED-BATCH GLYCEROL FERMENTATION DETERMINED BY MAXIMUM PRINCIPLE

Xie Dongming, Liu Dehua and Liu Tianzhong (State Key Lab of Biochemical Engineering, Institute of Chemical Metallurgy, Chinese Academy of Science, Beijing 100080; Department of Chemical Engineering, Tsinghua University Beijing 100084)   

  • Online:2000-12-30 Published:2000-12-30

OPTIMAL FEED STRATEGY FOR FED-BATCH GLYCEROL FERMENTATION DETERMINED BY MAXIMUM PRINCIPLE

  

Abstract: Optimal glucose feed strategy for glycerol fed-batch fermentation was investigated by Pontryagins maximum principle to maximize the final glycerol yield. The problem was solved by a nonsingular control approach by selecting the culture volume as the control variable, then the general optimal feed profile was numerically determined.

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