Abstract: The kinetic performance of isothermal piston flow desulfurization bed was studied on basis of the Equivalent Grain Model suggested by the authors that was used to discribing apparent kinetics of desulfurization with zinc oxide particles. The representation of both sulfur distribution curve and break-through curve was given. The effect of temperature, flow rate and concentration of sulfur compound on these curves was analyzed. After analysis of results obtained in a commercial scale desulfurizing bed of metal oxides, like zimc oxide, iron oxide, it was verified that the Equivalent Grain Model could be preferably used to describing the desulfurization process of metal oxides.