CIESC Journal ›› 2019, Vol. 70 ›› Issue (10): 4080-4088.DOI: 10.11949/0438-1157.20190342

• Material science and engineering, nanotechnology • Previous Articles     Next Articles

PMPS-b-PNIPAM copolymers synthesized by RAFT polymerization and their thermo-responsive nanoparticles

Xiaoyan ZHAO1,2(),Guorong SHAN1,2()   

  1. 1. State Key Laboratory of Chemical Engineering, College of Chemical and Biochemical Engineering, Zhejiang University, Hangzhou 310027, Zhejiang, China
    2. Institute of Zhejiang University-Quzhou, Quzhou 324000, Zhejiang, China
  • Received:2019-04-02 Revised:2019-05-29 Online:2019-10-05 Published:2019-10-05
  • Contact: Guorong SHAN

RAFT聚合制备PMPS-b-PNIPAM嵌段共聚物及温敏性纳米粒子

赵小燕1,2(),单国荣1,2()   

  1. 1. 化学工程联合国家重点实验室,浙江大学化学工程与生物工程学院,浙江 杭州 310027
    2. 浙江大学衢州研究院,浙江 衢州 324000
  • 通讯作者: 单国荣
  • 作者简介:赵小燕(1992—),女,博士研究生,xiaoyanzhao161@163.com

Abstract:

A series of molecular weight-controlled, narrow molecular weight distributions of 3-trimethoxysilyl methacrylate (MPS) and N-isopropyl acrylamide (NIPAM) block copolymers were synthesized by reversible addition-fragmentation chain transfer (RAFT) living radical polymerization. Temperature-sensitive silicon-containing nanoparticle are prepared by dispersing in aqueous solution. With the same chain length of hydrophobic segment PMPS, by changing the chain length of hydrophilic segment PNIPAM and the pH of the water solutions, the critical aggregation concentrations, the diameters and morphologies of the nanoparticles, and the phase separation behavior happening in the process of temperature variation were studied. Thermo-responsive and spherical nanoparticles were attained. The nanoparticles possessed advantages of both organics and inorganics. And they may have wide applications in many fields such as biomedicine, chemical catalysis, nanoreactors, dyes, coatings and so on.

Key words: polymers, silicane, nanoparticles, pH, hydrolysis

摘要:

利用可逆加成-断裂链转移(RAFT)活性自由基聚合合成了一系列分子量可控、分子量分布窄的甲基丙烯酸-3-三甲氧基硅丙酯(MPS)和N-异丙基丙烯酰胺(NIPAM)的嵌段共聚物,在水溶液中分散制备温敏性的含硅纳米粒子。保持疏水链段PMPS的长度恒定,改变亲水链段PNIPAM的长度,在不同pH的水溶液中进行实验,研究亲水链段长度、pH对聚合物的临界聚集浓度、纳米粒子的尺寸和形貌以及温度变化过程中的相分离行为的影响,得到尺寸较小、溶液稳定的温度响应性含硅纳米粒子,同时具有有机物和无机物的优良特点,在生物医学、化学催化、纳米反应器、染料涂料等多领域具有广泛的应用前景。

关键词: 共聚物, 硅烷, 纳米粒子, pH, 水解

CLC Number: