Abstract: With inreased critical discussions about potential toxicological effects of phthalates in the mid-nineties, esters of cyclohexane polycarboxylic acids are considered the most promising alternatives to phthalate as plasticizers. Hydrogenation of dibutyl phthalate (DBP) and diisobutyl phthalate (DIBP) using Ni as catalyst was studied by experiment. The products of hydrogenation were respectively dibutyl hexahydrophthalate and diisobutyl hexahydrophthalate. The appropriate reaction conditions for DBP hydrogenation were temperature 130℃, pressure 6.1 MPa and space velocity 1 h^-1. The conversion and selectivity of reaction were 99.93% and 92.47% respectively. The appropriate reaction conditions for DIBP hydrogenation were temperature 100℃, pressure 6.1 MPa and space velocity 0.5 h^-1. The conversion and selectivity of reaction were 99.70% and 90.42% respectively. Conversion and selectivity were chosen as reaction model parameters, and the synthesis and separation processes of dibutyl hexahydrophthalate and diisobutyl hexahydrophthalate was established by using Aspen Plus software. The purity of product was higher than 99%(mass). Process parameters have important guiding significance to commercialization of hydrogenation of DBP and DIBP.

Key words: hydrogenation, simulation, separation, plasticizer, dibutyl hexahydrophthalate, diisobutyl hexahydro-phthalate

摘要： 实验研究了在金属Ni催化剂上邻苯二甲酸二丁酯（DBP）加氢合成邻环己烷二甲酸二丁酯和邻苯二甲酸二异丁酯（DIBP）加氢合成邻环己烷二甲酸二异丁酯的反应。根据实验结果确定了DBP加氢反应的适宜条件为：温度130℃，压力6.1 MPa，空速1 h^-1。相应的反应转化率为99.93%，选择性为92.47%。DIBP加氢反应的适宜条件为：温度100℃，压力6.1 MPa，空速0.5 h^-1。相应的反应转化率为99.70%，选择性为90.42%。将反应转化率和选择性作为Aspen Plus中反应模型的参数，建立了邻环己烷二甲酸二丁酯和邻环己烷二甲酸二异丁酯合成与分离的流程，所得产品纯度可达99%（质量分数）以上。模拟得到的工艺参数对邻环己烷二甲酸二丁酯和邻环己烷二甲酸二异丁酯合成与分离流程的工业化具有指导意义。

关键词: 加氢, 模拟, 分离, 增塑剂, 邻环己烷二甲酸二丁酯, 邻环己烷二甲酸二异丁酯