Process simulation of tert-butyl acetate production by distillation column integrated with side reactors under different temperatures

doi:10.11949/j.issn.0438-1157.20150207

CIESC Journal ›› 2015, Vol. 66 ›› Issue (10): 4039-4046.DOI: 10.11949/j.issn.0438-1157.20150207

Previous Articles Next Articles

Process simulation of tert-butyl acetate production by distillation column integrated with side reactors under different temperatures

HUANG Yuxin¹, TANG Jihai¹, CHEN Xian¹, SONG Jianguo¹, CUI Mifen¹, FEI Zhaoyang², QIAO Xu²

1 Jiangsu Key Laboratory of Industrial Water-conservation &Emission Reduction, College of Chemistry and Chemical Engineering, Nanjing Tech University, Nanjing 210009, Jiangsu, China;
2 State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 210009, Jiangsu, China

Received:2015-02-09 Revised:2015-06-07 Online:2015-10-05 Published:2015-10-05
Supported by:
supported by the National Natural Science Foundation of China (21276126, 61203020), the Graduate Research and Innovation Projects in Jiangsu Province (SJZZ_0098) and the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).

不同温度反应与精馏集成生产醋酸叔丁酯的过程模拟

黄玉鑫¹, 汤吉海¹, 陈献¹, 宋建国¹, 崔咪芬¹, 费兆阳², 乔旭²

1 南京工业大学化学化工学院, 江苏省工业节水减排重点实验室, 江苏南京 210009;
2 南京工业大学材料化学工程国家重点实验室, 江苏南京 210009

通讯作者: 汤吉海, 乔旭
基金资助:
国家自然科学基金项目(21276126,61203020);江苏省普通高校研究生科研创新计划项目(SJZZ_0098);江苏高校优势学科建设工程项目。

Abstract

Abstract:

An advanced technology integrating a high-temperature distillation column with low-temperature side reactors(SRC) was proposed for tert-butyl acetate production via the additive esterification of acetic acid and isobutylene, since the reaction and separation required completely different operations. With a vapor boilup rate of 100 kmol·h^-1, acetic acid conversion of 99.9% and tert-butyl acetate selectivity of 97.0%, the effects of flow rate from distillation column to reactors, stage number of rectification zone, side-reactor number and interval stage number between inlet and outlet of the reactor were systemically investigated. The results demonstrated that a higher economy process could be achieved with a more optimized match between the reaction capability and the separation capability. The obtained results laid a foundation for design and optimization of the industrial SRC process.

Key words: reactive distillation, reactors, esterification, tert-butyl acetate, integration

摘要：

针对醋酸与异丁烯加成酯化可逆反应温度低、精馏分离温度高的特点,采用带侧反应器的反应精馏集成过程(SRC)建立了低温反应与高温精馏集成的醋酸叔丁酯生产新工艺。固定塔釜上升汽化量100 kmol·h^-1,规定新鲜醋酸进料的转化率达到99.9%、醋酸叔丁酯选择性达到97.0%,采用过程模拟考察了进入侧反应器的精馏塔采出量、精馏段塔板数、侧反应器进出口间隔塔板数和侧反应器台数等参数对合成醋酸叔丁酯的SRC过程的影响。模拟结果表明,醋酸与异丁烯加成酯化生产醋酸叔丁酯的SRC过程中只有反应能力与分离能力达到最佳匹配才能使单位产品的生产成本最小。研究结果为醋酸叔丁酯生产新工艺的放大设计与优化奠定了基础。

关键词: 反应精馏, 反应器, 酯化, 醋酸叔丁酯, 集成

CLC Number:

TQ021.8

HUANG Yuxin, TANG Jihai, CHEN Xian, SONG Jianguo, CUI Mifen, FEI Zhaoyang, QIAO Xu. Process simulation of tert-butyl acetate production by distillation column integrated with side reactors under different temperatures[J]. CIESC Journal, 2015, 66(10): 4039-4046.

黄玉鑫, 汤吉海, 陈献, 宋建国, 崔咪芬, 费兆阳, 乔旭. 不同温度反应与精馏集成生产醋酸叔丁酯的过程模拟[J]. 化工学报, 2015, 66(10): 4039-4046.

References 24

[1]	Faber W, Kirkpatrick D, Coder P, Li A, Borghoff S, Banton M. Subchronic, reproductive, and maternal toxicity studies with tertiary butyl acetate (TBAC) [J]. Regulatory Toxicology and Pharmacology, 2014, 68(3): 332-342.
[2]	Luo D, Corey R, Propper R, Collins J, Komorniczak A, Davis M, Berger N, Lum S. Comprehensive environmental impact assessment of exempt volatile organic compounds in California [J]. Environmental Science & Policy, 2011, 14(6): 585-593.
[3]	Montón J B, Muñoz R, Burguet M C, Torre J. Isobaric vapor-liquid equilibria for the binary systems isobutyl alcohol+isobutyl acetate and tert-butyl alcohol+tert -butyl acetate at 20 and 101.3kPa [J]. Fluid Phase Equilibria, 2005, 227(1): 19-25.
[4]	Shyamprasad K, Shamshuddin S Z M, Vasantha V T. Effective acetylation of alcohols, phenols and amines over mesoporous aluminophosphate solid acids under solvent free conditions [J]. Journal of Porous Materials, 2014, 21(6): 1079-1090.
[5]	Gu Y L, Shi F, Deng Y Q. Esterification of aliphatic acids with olefin promoted by Brønsted acidic ionic liquids [J]. Journal of Molecular Catalysis A: Chemical, 2004, 212(1/2): 71-75.
[6]	Trost B M. The atom economy - a search for synthetic efficiency [J]. Science, 1991, 254(5037): 1471-1477.
[7]	Karas L J. Ester preparation[P]: US, 5994578. 1999-11-30.
[8]	Yu Guocong(余国琮), Yuan Xigang(袁希钢), Li Genhao(李根浩). Review of papers on distillation research published in “CIESC Journal” in past 60 years [J]. CIESC Journal (化工学报), 2013, 64(1): 11-27.
[9]	Malone M F, Doherty M F. Reactive distillation [J]. Industrial & Engineering Chemistry Research, 2000, 39(11): 3953-3957.
[10]	Niesbach A, Fuhrmeister R, Keller T, Lutze P, Gorak A. Esterification of acrylic acid and n-butanol in a pilot-scale reactive distillation column-experimental investigation, model validation, and process analysis [J]. Industrial & Engineering Chemistry Research, 2012, 51(50): 16444-16456.
[11]	Xiao Wu(肖武), Li Mingyue(李明月), Ruan Xuehua(阮雪华), He Gaohong(贺高红), Du Jian(都健). Optimization of ethyl acetate process conditions for sodium bisulfate fluidized catalytic distillation using response surface methodology [J]. CIESC Journal (化工学报), 2014, 65(11): 4465-4471.
[12]	Degarmo J L, Parulekar V N, Pinjala V. Consider reactive distillation [J]. Chemical Engineering Progress, 1992, 88(3): 43-50.
[13]	Ding Lianghui(丁良辉), Tang Jihai(汤吉海), Cui Mifen(崔咪芬), Chen Xian(陈献), Bo Cuimei(薄翠梅), Qiao Xu(乔旭). Analysis and comparison of RD and SRC involving the consecutive reaction of chlorination of toluene [J]. CIESC Journal (化工学报), 2013, 64(9): 3277-3284.
[14]	Baur R, Krishna R. Distillation column with reactive pump arounds: an alternative to reactive distillation [J]. Chemical Engineering and Processing, 2004, 43: 435-445.
[15]	Ye J C, Li J, Sha Y, Lin H D, Zhou D W. Evaluation of reactive distillation and side reactor configuration for direct hydration of cyclohexene to cyclohexanol [J]. Industrial & Engineering Chemistry Research, 2014, 53: 1461-1469.
[16]	Bisowarno B H, Tian Y C, Tade M O. Application of side reactors on ETBE reactive distillation [J]. Chemical Engineering Journal, 2004, 99(1): 35-43.
[17]	Kaymak D B, Luyben W L. Design of distillation columns with external side reactors [J]. Industrial & Engineering Chemistry Research, 2004, 43: 8049-8056.
[18]	Kaymak D B, Luyben W L. Optimum design of a column/side reactor process [J]. Industrial & Engineering Chemistry Research, 2007, 46(15): 5175-5185.
[19]	Gangadwala J, Kienle A. MINLP optimization of butyl acetate synthetsis [J]. Chemical Engineering and Processing, 2007, 46: 107-118.
[20]	Ding Lianghui(丁良辉), Tang Jihai(汤吉海), Cui Mifen(崔咪芬), Chen Xian(陈献), Bo Cuimei(薄翠梅), Qiao Xu(乔旭). Optimum design of coupled atmospheric reaction—vacuum distillation technology for benzyl chloride production [J]. CIESC Journal (化工学报), 2011, 62(8): 2323-2327.
[21]	Ding L H, Tang J H, Cui M F, Bo C M, Chen Xian, Qiao X. Optimum design and analysis based on independent reaction amount for distillation column with side reactors: production of benzyl chloride [J]. Industrial & Engineering Chemistry Research, 2011, 50(19): 11143-11152.
[22]	Kim Y, Pokki J P, Rehak K, Matous J, Aittamaa J. Excess enthalpy and vapor-liquid equilibrium at atmospheric pressure for the binary systems 2-methyl-2-propanol+2,4,4-trimethyl-1-pentene and 2-butanol+ 2,4,4-trimethyl-1-pentene [J]. Journal of Chemical and Engineering Data, 2004, 49(2): 246-250.
[23]	Douglas J M. Conceptual Design of Chemical Processes [M]. New York: McGraw-Hill, 1988: 345-350.
[24]	Lu Enxi(陆恩锡), Li Xiaoling(李小玲). Retrograde distillation [J]. Chemical Engineering (China) (化学工程), 2010, 38(4): 97-102.

Process simulation of tert-butyl acetate production by distillation column integrated with side reactors under different temperatures

不同温度反应与精馏集成生产醋酸叔丁酯的过程模拟

PDF (PC)

Knowledge

Cited

Abstract

Cite this article

share this article

References 24

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	Jie CHEN, Yongsheng LIN, Kai XIAO, Chen YANG, Ting QIU. Study on catalytic synthesis of sec-butanol by tunable choline-based basic ionic liquids [J]. CIESC Journal, 2023, 74(9): 3716-3730.
[2]	Zhewen CHEN, Junjie WEI, Yuming ZHANG. System integration and energy conversion mechanism of the power technology with integrated supercritical water gasification of coal and SOFC [J]. CIESC Journal, 2023, 74(9): 3888-3902.
[3]	Yue CAO, Chong YU, Zhi LI, Minglei YANG. Industrial data driven transition state detection with multi-mode switching of a hydrocracking unit [J]. CIESC Journal, 2023, 74(9): 3841-3854.
[4]	Guixian LI, Abo CAO, Wenliang MENG, Dongliang WANG, Yong YANG, Huairong ZHOU. Process design and evaluation of CO₂ to methanol coupled with SOEC [J]. CIESC Journal, 2023, 74(7): 2999-3009.
[5]	Yuanzhe SHAO, Zhonggai ZHAO, Fei LIU. Quality-related non-stationary process fault detection method by common trends model [J]. CIESC Journal, 2023, 74(6): 2522-2537.
[6]	Lanhe ZHANG, Qingyi LAI, Tiezheng WANG, Xiaozhuo GUAN, Mingshuang ZHANG, Xin CHENG, Xiaohui XU, Yanping JIA. Effect of H₂O₂ on nitrogen removal and sludge properties in SBR [J]. CIESC Journal, 2023, 74(5): 2186-2196.
[7]	Jianhua ZHANG, Mengmeng CHEN, Yawen SUN, Yongzhen PENG. Efficient nitrogen and phosphorus removal from domestic wastewater via simultaneous partial nitritation and phosphorus removal combined Anammox [J]. CIESC Journal, 2023, 74(5): 2147-2156.
[8]	Xiaoyong GAO, Fuyu HUANG, Wanpeng ZHENG, Diao PENG, Yixu YANG, Dexian HUANG. Scheduling optimization of refinery and chemical production process considering the safety and stability of scheduling operation [J]. CIESC Journal, 2023, 74(4): 1619-1629.
[9]	Sheng’an ZHANG, Guilian LIU. Multi-objective optimization of high-efficiency solar water electrolysis hydrogen production system and its performance [J]. CIESC Journal, 2023, 74(3): 1260-1274.
[10]	Haiou YUAN, Fangjun YE, Shuo ZHANG, Yiqing LUO, Xigang YUAN. Synthesis of heat-integrated distillation sequences with intermediate heat exchangers [J]. CIESC Journal, 2023, 74(2): 796-806.
[11]	Kun LIU, Yuan YIN, Wenqiang GENG, Haotian XIA. Study on nitrogen fixation performance and mechanism analysis of dielectric barrier discharge under different operating parameters [J]. CIESC Journal, 2022, 73(9): 4045-4053.
[12]	Ruining HE, Yun ZOU, Meng SHI, Yang LI, Jing XU, Zhangfa TONG. Preparation of supported ionic liquid [HSO₃-BMIM][HSO₄]/SiO₂ and its catalytic property in the esterification of acetic acid and ethanol [J]. CIESC Journal, 2022, 73(9): 3880-3894.
[13]	Hanlin YAO, Zhong XIN. Research on flow behavior of liquid-phase precipitation reaction in the tubular microchannel reactor [J]. CIESC Journal, 2022, 73(8): 3518-3528.
[14]	Jing WAN, Lin ZHANG, Yachao FAN, Xiemin LIU, Peicheng LUO, Feng ZHANG, Zhibing ZHANG. Bioreactor scale-up simulation and experimental study based on mesoscale PBM model [J]. CIESC Journal, 2022, 73(6): 2698-2707.
[15]	Qiwang HOU, Zhaolun WEN, Zhonglin ZHANG, Yegang LIU, Jingxuan YANG, Dongliang CHEN, Xiaogang HAO, Guoqing GUAN. Design and evaluation of a coal-based polygeneration system with carbon cycle [J]. CIESC Journal, 2022, 73(5): 2073-2082.