关键词:

医用聚氨酯, 亲水性, 表面改性, 血液相容性

Abstract:

Interaction of surface with water plays a key role in the blood compatibility of biomedical materialIn this article, the research progress in hydrophilic functionalization for the surface of medical polyurethane as the typical model of biomedical polymer was reviewed, and the functions of water to block nonspecific adsorption of blood proteins and the formation of thrombosis were also discussedThe behavior of water molecules and their effect on the blood compatibility of the modified polyurethane, functionalized by the active materials such as hydrophilic vinyl monomer, polyethylene glycol and its derivates, heparin and zwitterionic materials, was exploredThe knowledge of the functionalities of water and hydration layer during the interactions between blood and biomedical materials would benefit surface design and application of biocompatible polymer

Key words:

医用聚氨酯, 亲水性, 表面改性, 血液相容性