化工学报 ›› 2005, Vol. 56 ›› Issue (8): 1547-1551.

• 生物化学工程、制药、食品和天然产物加工 • 上一篇    下一篇

高压静电法制备单分散性的海藻酸钙微胶珠

曲蓓蓓;于炜婷;刘袖洞;包德才;宋晓炎;綦文涛;马小军   

  1. 中国科学院大连化学物理研究所 ,辽宁 大连 116023 ;中国科学院研究生院,北京 100039;浙江大学药学院, 浙江 杭州 310027
  • 出版日期:2005-08-25 发布日期:2005-08-25

Preparation of monodispersed calcium alginate gel beads in high voltage electrostatic field

QU Beibei;YU Weiting;LIU Xiudong;BAO Decai;SONG Xiaoyan;QI Wentao;MA Xiaojun
  

  • Online:2005-08-25 Published:2005-08-25

关键词: 高压静电场, 海藻酸钠, 胶珠, 单分散

Abstract: In this paper, the effect of operation parameters on the monodispersity of calcium-alginate gel beads prepared in high-voltage electrostatic field were analyzed.The parameters included the applied potential (U),the distribution of electrostatic field, the frequency and the flow rate of solution through the capillary. Furthermore, the process is analyzed with the theory of jet break-up in electrostatic field. The result showed that the modified symmetrical electrostatic field was more advantageous in preparing the monodispersed gel beads than the traditional method. Meanwhile,gel beads with good monodispersity(CV<20%) and stability without aggregation were produced under a range of applied potential (U), frequency and flow rate of solution through the capillary.

Key words: 高压静电场, 海藻酸钠, 胶珠, 单分散