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Physical and Hydrodynamic Properties of Spherical Cellulose-Titanium Dioxide Composite
Matrix for Expanded Bed Adsorption

LEI Yinlina; LIN Dongqianga; YAO shanjinga; LIU Zuozhenb; ZHU Ziqianga   

  1. a Department of Chemical and Biochemical Engineering, Zhejiang University, Hangzhou 310027,
    China
    b State Key Laboratory of Bioreactor Engineering, East China University of Science and
    Technology, Shanghai 200237, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2003-04-28 Published:2003-04-28

球形纤维素-钛白粉复合基质的扩张床流体混合特性

雷引林a; 林东强a; 姚善泾a; 刘坐镇b; 朱自强a   

  1. a Department of Chemical and Biochemical Engineering, Zhejiang University, Hangzhou 310027,
    China
    b State Key Laboratory of Bioreactor Engineering, East China University of Science and
    Technology, Shanghai 200237, China

Abstract: Expanded bed adsorption (EBA) has been widely used in industrial downstream bioprocessing.
Solid matrix is the principal pillar supporting the successful application of EBA. A novel
spherical cellulose-titanium dioxide composite matrix was prepared through the method of
water-in-oil suspension thermal regeneration. Its typical physical properties were wet
density 1.18g.cm-3, diameters in the range of 100-300μm, porosity 85.5%,and water content
72.3%. Expansion characteristics and liquid mixing performance of the matrix in expanded
bed were investigated using water and 10% (by mass) glycerol solution as mobile phases. The
results indicate that the custom-assembled matrix has a stable flow hydrodynamics and
exhibits the same degree of liquid-phase mixing or column efficiency as the commercially
available Streamline adsorbent.

Key words: expanded bed adsorption, matrix, cellulose, titanium dioxide

摘要: Expanded bed adsorption (EBA) has been widely used in industrial downstream bioprocessing.
Solid matrix is the principal pillar supporting the successful application of EBA. A novel
spherical cellulose-titanium dioxide composite matrix was prepared through the method of
water-in-oil suspension thermal regeneration. Its typical physical properties were wet
density 1.18g.cm-3, diameters in the range of 100-300μm, porosity 85.5%,and water content
72.3%. Expansion characteristics and liquid mixing performance of the matrix in expanded
bed were investigated using water and 10% (by mass) glycerol solution as mobile phases. The
results indicate that the custom-assembled matrix has a stable flow hydrodynamics and
exhibits the same degree of liquid-phase mixing or column efficiency as the commercially
available Streamline adsorbent.

关键词: expanded bed adsorption;matrix;cellulose;titanium dioxide